Metropolitan Opera cancels 2020-2021 season resulting from Covid-19 considerations

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This September 2020 photo provided by Johnson & Johnson shows a single-dose COVID-19 vaccine being developed by the company. 
This September 2020 picture supplied by Johnson & Johnson exhibits a single-dose COVID-19 vaccine being developed by the corporate.  Cheryl Gerber/Courtesy of Johnson & Johnson/AP

Johnson & Johnson’s Covid-19 vaccine candidate begins part three trials in the USA on Wednesday. Trials for the single-dose vaccine, which makes use of a human adenovirus, will embody as much as 60,000 grownup individuals at practically 215 websites within the US and internationally. 

 The vaccine candidate was developed by Janssen Pharmaceutical Corporations, a subsidiary of Johnson & Johnson. Part three trials will start instantly, with the primary individuals receiving doses Wednesday, Johnson & Johnson Chief Scientific Officer Dr. Paul Stoffels mentioned on a name with reporters Tuesday.

Preliminary findings from the vaccine’s part half trials within the US and Belgium recommend the vaccine provokes an immune response and is secure sufficient to maneuver into large-scale trials. 

Part three trials will look at the security and effectiveness of a single dose in opposition to a placebo to stop symptomatic Covid-19. The truth that the trial will look at the efficacy of a single dose of the vaccine, as a substitute of two doses, ought to expedite outcomes, mentioned Stoffels.

Trials will run in Argentina, Brazil, Chile, Colombia, Mexico, Peru, South Africa and the USA. Johnson & Johnson intends to run a separate part three trial in collaboration with the UK authorities to look at the effectiveness of two doses

If the vaccine is confirmed secure and efficient, Johnson & Johnson mentioned it expects the primary doses to be out there for emergency use authorization from the US Meals and Drug Administration by early 2021. 

The place issues stand: Moderna, Pfizer/BioNTech and AstraZeneca even have Covid-19 vaccine candidates in Part three trials in the USA, though AstraZeneca’s trial is presently paused.

Johnson & Johnson’s part three trial is being performed in collaboration with Operation Warp Pace, the federal authorities’s coronavirus vaccine effort.

Dr. Gupta discusses Johnson & Johnson’s vaccine:

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